"We should play like that every game," Dragic said. "We should play like that against everybody, even if they are last in the standings."
Phoenix led by 13 at the half, as many as 24 in the third quarter and 26 in the fourth.
Green and Plumlee came to the Suns along with a first-round draft pick in a trade that sent Luis Scola to Indiana in the offseason. Scola scored five on Wednesday night.
The Suns shot 54 percent, including 11 of 16 from 3-point range. The Pacers committed 21 turnovers, resulting in 27 Phoenix points. The Suns had 10 turnovers for 10 Indiana points.
The Suns led 62-49 at the break.
The onslaught started when Phoenix opened the second quarter with a 14-2 run that put the Suns ahead 44-31. Frye and Green each sank a 3 in the surge.
The Pacers, having trouble with some the Suns' best offensive pressure of the season, never got closer than nine the rest of the half.
Tucker's 3-pointer from the corner put Phoenix ahead 59-45, then Dragic made one of two free throws and it was 60-45. George sank a jumper, then with 9.8 seconds left, Dragic made an 18-footer and the Suns were up 62-47. George's step-back 21 footer at the buzzer cut it to 62-49. Green scored 18 in the first half, George 14.
The Suns turned it up a notch to start the second half, opening with a 10-2 run to lead 72-51 on Tucker's basket. When Dragic sank a 3 moments later, Phoenix led 79-55 with 7:12 left in the third quarter. The Suns led 96-79 entering the fourth.
"I thought our guys really focused at the start of the third quarter to really build that lead, rather than let them come right back in the game," Suns coach Jeff Hornacek said.
The Pacers scored the first four points of the final quarter to make it 96-83, but Ish Smith scored on a drive, Morris sank consecutive 3s and Phoenix led 105-83 in one of the most raucous environments at US Airways Center this season.