Neither John Fox nor Chuck Pagano were prepared to say how costly this game might be to their teams. But the two biggest injury concerns are franchise cornerstones. Denver lost cornerback Champ Bailey late in the first half when his left foot got caught in a scrum trying to take down running back Trent Richardson. Bailey angrily walked off the field after re-injuring the same foot that kept him out of the first five games. He did not return. The Colts lost Reggie Wayne in the fourth quarter with a sprained right knee that sent him to the locker room in tears. And while the Colts are hoping for the best, Wayne is expected to undergo an MRI on Monday.